Monday, February 18, 2008

Self Evaluation

Self Evaluation


1. What were the three aspects of the assignments I've submitted that I am most proud of?
I am most proud of my work on my compendium review because I found by doing the reviews I was understand the chapters and terms by writing or typing it out. It was a lot of reading but I managed.

2. What two aspects of my submitted assignments do I believe could have used some improvement?

my ethical essay could use my time on and my DNA for my lab. when I first read the lab I though I could manage doing it but once I started it took me awhile to figure out what I was doing and how I wanted it to be done.

3. What do I believe my overall grade should be for this unit?

I put a lot of time and focus on this unit and it was a BIG unit. I did all the work, all the reading and time to do the labs. But I got my book two weeks late and I had to rush myself to do the assignments. My Overall grade I would give myself would be a B+.

4. How could I perform better in the next unit?

For me it would be my time management. I would read the chapters and understand it more and will make more of an effort on my essay.

5. At what moment during this unit did you feel most engaged with the course?

The cell model and the genetics.

6. At what moment unit did you feel most distanced from the course?
I would have to say the DNA part. Though I know it's important to know about I just could not get into the reading to much.

7.What action that anyone (teacher or student) took during this unit that find most affirming and helpful?

I would say the teacher's human biology website. I found everything I needed on his site to complete my assignments.

8. What action that anyone (teacher or student) took during this unit did you find most puzzling or confusing?

None.

9. What about this unit surprised you the most? (This could be something about your own reactions to the course, something that someone did, or anything else that occurs to you.)

That I got really interested in the cell and cancer chapters. at first I thought the cell was a boring topic but doing the "make your own cell" and reading the chapter really help me understand the cell and its purpose.

Ethical Essay-Cloning

What is Cloning?
Cloning is the production of genetically identical copies of DNA, cells, or organisms through an asexual means. There are three types of cloning: recombinant DNA technology, reproductive cloning and therapeutic cloning. There are many debates of cloning of animals and human. Cloning can help stop extinction of other animals and even bring some back to life that is extinct like the mammoth. Dolly the sheep who was the first mammal that was cloned was a celebrity in the science world. Dolly lived to be 6 and died with lethal injection. Dolly suffered cancer and arthritis but appear normal.
Cloning of animals can help with the extinction problems or mating issues. There are many researchers that are trying to save the animals from extinction and cloning can help solve this problem for the animals and humans.
Cloning can also be useful in the future for humans. Cloning can help produce organs for people who need a transplant or have diseases that can be a cure like Alzheimer or Parkinson’s.
The cloning of humans is in the question, whether or not if it is safe or necessary. What would be that purpose? I cannot image having another person that is the same as me walking around. Cloning should be only used for realistic reasons not just to seeing a cloned human. Cloning is not close to being safe and has a high percentage of failing imaging cloning a person and giving them life and watching them die because they got an infection or cancer.
In the future I see cloning being very important because people would not have to worry about going hungry if the climates change, the animals will always be around and people would not have to be sick, they could get a new organ. I think some scientist would still like to clone a human why else would they have a law against it if someone weren’t trying to. Someday they might but I know once it does happen there will be a lot of debating going on.

Compendium Review Part II


Chapter 18
Chromosomes and The Cell Cycle
Chromosomes occur in 23 pairs in body cells.
• A Karyotype- is a visual display of a person’s chromosomes.
• The Cell Cycle- the cell cycle has two parts: Interphase & cell division.
-Interphase- Most of the cell cycle spends it’s time during interphase. It has three phases. The G (one) stage which double its organelles and occurs before DNA synthesis; S stage is when DNA replication and is during DNA synthesis; then the G (two) stage is the cell synthesizes the proteins needed for cell division and it occurs after DNA synthesis.

Cell division-After the cell enters interphase it then goes to cell division. The cell division has two stages. First of all the cell enters mitosis. Mitosis is a type of nuclear division. The second stage is cytokinesis is a division of the cytoplasm.






Comparison of Meiosis and Mitosis
• Meiosis and mitosis both have the same type of nuclear division.
• Mitosis has no pairing of chromosomes, is out of control when cancer occurs, is duplication division, it’s cell are exactly like the parent cell and is part of the cell cycle.
• Meiosis results into four daughter cells, is reduction division, it results in cells that are genetically different from the parent cell and is involved in gametogenesis.

Chromosome Inheritance
Meiosis is part of gametogenesis and contributes to genetic diversity. A person can be born with to many or too few autosomes or sex chromosomes due to nondisjunction during meiosis. Nondisjunction occurs when both members of a homologous pair go into the same daughter cell and fail to separate and both daughter chromosomes go into the same gamete. The most common known autosomal trisomy is Down syndrome.
Some can be born with to many or to few sex chromosomes such as turner syndrome, klinefelter syndrome, poly-X females and Jacobs syndrome. Chromosomal mutations can produce chromosomes with deleted, duplicated, inverted, or translocated segment. These syndromes are deletion syndromes and translocation syndromes.

Chapter 19

Cancer Cells
There are different type of characteristics of cancer cells: Cancer cells lack differentiation, cancer cells have abnormal nuclei, cancer cells from tumors, cancer cells have no need for growth factors, cancer cells gradually become abnormal and cancer cells undergo angiogenesis and metastasis. Mutation genes lead to uncontrollable growth in two types: Proto-oncogenes and tumor-suppressor genes. There are different types of cancer but the most common cancer is: breast cancer, prostate cancer, and colorectal cancer.

Causes and Prevention of Cancer
Some cancer can be heredity that is passed down from family like breast cancer or retinoblastoma tumor. Cancer is determined by a person’s genetic profile or exposure to environmental carcinogens. Cancer that is caused by the environmental factors is from radiation, tobacco smoke or pollutants. Also certain viruses can cause cancer like hepatitis B and C.
There are preventions of getting cancer like your lifestyle. Nutrition is a way to help prevent cancer, exercise, eating habits, no smoking or no drinking and to eat more fruit and vegetables.
Diagnosis of Cancer
The earlier a cancer is diagnosed the more likely it can be treated. A Pap test for cervical cancer, mammogram for breast cancer and some blood test can also detect cancer/tumors. If cancer does exist biopsy and imaging is used to confirm the diagnosis of cancer.
Treatment of Cancer
Today there are treatments for cancer and are different from one another. Surgery is used to removed the cancer but a person is at risk of having a relapse if a cancer cell is still in the body, radiation is used to kill cancer cells but had side affects and chemotherapy which is used to treat the whole body so no cancer cells can spread anywhere else in the body. There are also newer therapies that are being used to treat cancer.


Chapter 20
Patterns of Genetic Inheritance
Genotype and Phenotype
Genotype-refers to the genes of the individual
Phenotype-The physical appearance (the characteristics) associated with these alleles.
Homozygous dominant- (EE) has the dominant phenotype.
Homozygous recessive- (ee) has the recessive phenotype.
Heterozygous- (Ee) has the dominant phenotype.
One and two Trait Inheritance
The punnett square is useful to find out all the possible types of gametes.
The first step to doing is to determine the genotype and gametes.
Gametes: (D), (Pw)
Genotype: (Ll), (LlGg)
The reason why theses are different is that gametes cannot have the same letting such as (Aa) or (AaLl).

Beyond Simple Inheritance Patterns
In some patterns of inheritance, the alleles are not just dominant or recessive.
• Polygenic Inheritance- like skin color and height, are controlled by more than one set of alleles.
• Incomplete Dominance and Codominance- the heterozygote is intermediate between the two homozygotes. In codominance both dominant alleles are expressed equally.
• Multiple Allele Inheritance- The multiple allele inheritance pattern is exemplified in humans by blood type inheritance. Everyone has two out of three possible alleles: 1(a), I (b). both are expressed.
Sex-Linked Inheritance
Many genes on the X chromosomes, such as those that determine normal vision as opposed to color blindness, are unrelated to the gender of the individual.
• X linked Recessive Disorder of Interest- Color blindness, muscular dystrophy, and hemophilia.






Chapter 21
DNA Biology and Technology
DNA and RNA structure and Functions
DNA (deoxyribonucleic acid) is the genetic material and the DNA is largely found in the chromosomes, located in the nucleus of a cell.
DNA is a double helix
Each strands is a polynucleotide

Gene Expression
Gene expression leads to the formation of a product, usually a protein. Proteins differ by the sequence of their amino acids. Gene expression requires transcription and translation.
• Transcription
• Translation
Genomics
• A person’s genome can be modified
• Functional and comparative genomics
• Proteomics and Bioinformatics are new endeavors
DNA Technology
• Genes can be isolated and cloned
1. Gene cloning can be done to make copies of the same gene.
• Specific DNA sequences can be cloned
1. DNA fingerprinting
• Biotechnology Products
1. From bacteria
2. From Plants
3. From animals





CELL MODEL

This assignment is about understanding the cell, DNA and Mitosis. I constructed my own model of a cell, mitosis and DNA. First of all lets look at a few pictures of what a Cell, DNA and Mitosis look like, and then well see my models.



This Model is of a cell and what is inside a cell












This is a DNA double helix and what it looks like. If you straighten it out it looks more like a ladder.













DNA replication-When cells divide and each new cell gets an exact copy of DNA.













My Cell

First of all what is a Cell? Cells are basic unit of life, cells are small and can be seen through a microscope. So what is in a cell and how do they work.

• Plasma membrane- (A Pink bowel)- The outer surface of a cell that regulates what can enter the cell and what can exit.
• Mitochondrion- (Blue Moon Sand)- Organelle that carries out cellular respiration, producing ATP molecules.
• Nucleolus- (Cotton ball)- Dark staining, spherical body in the cell nucleus that produces ribosomal subunits.
• Nucleus- (Pink Moon Sand)- stores genetic information.
• Rough ER- (off white yarn)-
• Smooth ER- (Stringers with hearts)-
• Vesicle- (Thumbtacks)- Small, membrane-bounded sac that stores substances within a cell.
• Lysosome- (BB balls)- membrane-bound vesicle that contains hydrolytic enzymes for digesting macromolecules.
• Golgi Apparaus- (Green yarn)- Organelle, consisting of saccules and vesicles, that processes, packages, and distributes molecules about or form the cell.
• Centrioles- (cap of a marker)- Cellular structure, existing in pairs, that possibly organizes the mitotic spindle for chromosomal movement during mitosis and meiosis.


Mitosis
Mitosis is duplication division. The nuclei of the two new cells have the same number and kinds of chromosomes as the ell that divides.Strands- necklace beads
Molecule-highlighted paper

DNA
DNA is the genetic material and that DNA is largely found in the chromosomes, located in the nucleus of a cell.

This following picture is a DNA double helix; it is composed of two strands that spiral about each other.

Items used for this Project

Sunday, February 17, 2008

Genetic inheritance

Genetic inheritance is important to the evolution of life. It makes us who we are today. How each of our family is different from another but still the same in other ways. Each parent passes down a characteristics which their parents pass down to them and they will pass down to their children in the future and so on.

What do these terms mean?

Genotype-refers to the genes of the individuals
Phenotype-refers to the physical characteristics
Allele-Alternative form of a gene; allele occurs at the same locus on homologous chromosomes.
Dominant allele- Allele that exerts its phenotypic effect in the heterozygote; it masks the expression of the recessive allele.
Recessive allele- Allele that exerts its phenotypic effect only in the homozygote; its expression is masked by a dominant allele.

This is my dragon at the end of the assignment, both looking exactly the same but with different type of phenotype. In order to get the dragons to look the same I had to change a few chromosome alleles












This is scenario 5. The first three offspring look the same but the last one the fourth looks different. The first one is (LL), second (Ll), third (Ll), and fourth (ll). So the First three are heterozygous long-winged fly and the fourth fly is not













Each parent gives it own characteristic to his or her children. If the parents are heterozygous each of their children has a 75% chance of having their parent’s phenotype and 25% of having the recessive phenotype. I remember back in middle school doing a project with our families whether or not we could roll our tongues. Since my older sister could not roll her tongue that meant that one of my parent’s could not either. At the end it was my dad who could not roll his tongue. My mom, sister and I could roll our tongues. There are other characteristics we could all try to conclude: if we have long fingers, blue or green eyes, tall or short or brown or black hair.
The punnett square is a great way to determine every possible combination of gametes.

The Lab:
To the two labs about genetic of a dragon and fruitfly and to come up with the correct outcome.
In Conclusion:

Knowing where we came from, what genes were passed down to others is very important. It lets everyone know what genes they can pass down to their future children. There some families that have genetic disorders that can be passed down to them and knowing what is in your own gene is important.

Friday, February 15, 2008

Compendium Review

1. Exploring Life and Science
• The Characteristics of Life- All living things are called organisms because each shares common characteristics. Each has the same level of organizations such as atoms, molecules, cells, tissues, organs, organ system, organism, populations, community, ecosystems, biosphere and all grow and develop. Life has an evolutionary history meaning that all organism share the same characteristic of life because their ancestry can be traced to cells but each organism are diverse from each other because they each adapt to life in a different ways.• Human Related to Other Animals- All living things are categorize in kingdoms. Human are vertebrates in the kingdom of animalia. Humans are closed related to apes but did not evolve from apes. Since all living things are included in the biosphere human are probably the biggest threats to the biosphere.
• Science as a Process- To understand science it takes time and research. A scientific method is making an observation, making a hypothesis, experiments, conclusion and the developing a theory with the findings.
• Making Sense of a Scientific Study-making a scientific study can take months or years and can change with new findings and other studies. Graphs are usually included with studies. The data is part of the experiment usual a bar or line graph are used to determine the outcome of the experiment. The hypothesis has a chance of having a different outcome at the end and can alter.
• Science and Social Responsibility-Being part of the biosphere, being part of life, everyone is responsible for life and out earth. Today there are many technology and scientists are gaining a better understand about environment, animals, plants and how we can better our future for living.

2. Chemistry of Life

• From Atom to Molecules- Elements is one of the basic building blocks of matter, the human body is composed with four elements: carbon, nitrogen, oxygen, and hydrogen. An atom is the smallest unit of an element. Even though an atom is very small to the human eye it contains even smaller subatomic particles-protons (+charge), neutrons and electrons (-charge). Atoms bond with another form of chemical unit called the molecules. There are two types of bonds, a Ionic bond (ions-+and-charges) and a covalent bonding.
• Water and Living things- Water is the most abundant molecules in living organisms and water is a polar molecule. The human body (blood fills our arteries and veins) is 92% water. Water has different properties such as; water is liquid, water heats and freezes slowly, frozen water is less dense that liquid water, so ice floats on water, water is cohesive and fills tubular vessels, water is also universal solvent, and has a neutral pH. The interesting part about this section was the topic acid and it’s effect. Acid can effect out environment such as rain. Because of burning gasoline (cars) acid is in the air that rises and comes back down with the rain, leaving it hard for crops to grow to their full growth and casing damages to historical statues.
• Molecules of Life- There are four categories of organic molecules, which are carbohydrates, lipids, proteins, and nucleic acid and are all macromolecules that each contains subunits.
• Carbohydrates-Carbohydrates are quick and short-term energy storage in all livings things.
• Lipids- Lipids are fat and oils, which function in long-term energy storage. The Fatty acids can be saturated or unsaturated.
• Proteins- Proteins are important in the structure and functions of cells. Their functions are: support, enzymes, transport, defense, hormones and motion. Proteins are macromolecules with amino acid subunit.
• Nucleic Acids- There are two type of nucleic acid, DNA and RNA. Each DNA has different genes.
3. Cell Structure and Function
• What is a Cell? Everything with life is composed with cells and is very small. Most cells can be seen through a microscope. The reason why cells are so very tiny is that the surface-area-to-volume radio of a cell.
• How cells are organized- A cell is surround by a plasma membrane and has a central nucleus. Between the plasma membrane and central nucleus is a cytoplasm that contains various organelle and each have a specific function.






• The Plasma membrane and how Substance Cross it- All cells are surrounded by an outer plasma membrane and are the boundaries between the outside and inside of a cell.


• The Nucleus and the Production of Protein- the nucleus stores genetic information. Each person has different type of genes theses genes are DNA.
• The Cytoskeleton and Cell Movement- The cytoskeleton contains three types of fiber: microtubules, actins filaments and intermediate filaments. All each help maintain the cell’s shape and allows organelles to move about the cell.

-Cilia and flagella are both part of movement and contain microtubules.
• Mitochondria and Cellular Metabolism-




















Mitochondria and cellular metabolism are often called the powerhouses of the cell. Mitochondria have an inner membrane that forms cristae, which project into the matrix.

4. Organizations and Regulation of Body and Systems-
Types of Tissues- A tissue is composed of specialized cells of the same type that perform a common function in the body. There are four major types that are: connective tissue, muscular tissue, nervous tissue and epithdial tissue.
-Cancer is classified to the type of tissue from which they arise.
Connective tissue Connects and Supports- There are three type of connective tissue: fibrous, supportive tissue and fluid connective tissue.
-The fibrous connective tissue has two tissues and they are loose fibrous and dense fibrous connective tissues.
-The loose fibrous create loose and opens framework. It supports main internal organs like the lungs, arteries and the urinary bladder. It forms a protective covering the organs like the muscles, blood vessels and nerves.
-The dense fibrous connective tissue contains many collagen fibers that are packed together. It has more specific functions and is located in the tendons that connect muscle to bone. Ligaments connect bones to other bones to joints.
Supportive connective tissue-There is three types of cartilage: hyaline cartilage, which is the most common and contains fine collagen fibers. It is found in the nose and the end of the ribs. The fetal skeleton contains this hyaline cartilage but later it is replaced with bones. The elastic cartilage is an elastic fibers and is found in the outer ear also is more flexible. Fibro cartilage has a matrix (ground substance and fibers) containing collagen fibers. It is found in structures that withstand tension and pressure, like in the wedges in the knee joint.
-Bone- is the most rigid connective tissue. The compact bone makes up the shaft of the long bone. The end of the long bone contains spongy bone. The spongy bone is designed for strength but is lighter than the compact bone.
Fluid connective tissue- The body has two types of fluid, blood and lymph. Blood is located in the blood vessels and consisted of formed elements and plasma. The lymph contains white blood cells and carried by lymphatic vessels and is derived from tissue fluid.
Muscular Tissue Moves the Body- the muscular tissue is composed by cells called muscle fibers. There is three type of vertebrate muscles tissue: the skeletal, smooth and cardiac.
Skeletal muscle Its function is the movement of the body, is voluntary and has striated (or striped appearance) cells. It has multiple nuclei and is attached to the skeleton.
Smooth muscle its function is in movement of substance in lumen of the body (intestine, bladder and other internal organ), it is involuntary and has spindle-shaped cells each with single nucleus. It is found in blood vessel walls and walls of the digestive tract.
Cardiac muscle its function is pumping blood and is located in the walls of the heart. It has branching striated cells each with a single nucleus and it is involuntary. It has combine features of smooth and skeletal muscles.
Nervous Tissue Communicates- Nervous tissue consists of nerve cells called neurons and neuroglia, the cells that support and nourish the neurons.
Neurons is a cell that has three parts: dendrites, a cell body, and an axon.
-Dendrates is an extension that receives signal from sensory receptors or other neurons.
-The cell body contains most of the cell’s cytoplasm and the nucleus.
-An axon is an extension that conducts nerve impulses.
Neuroglia are cells that outnumber neurons nine to one and take p more than half the volume of the brain. It support and nourish neurons and form myelin sheaths. They are found in the brain.
Epithelial Tissue Projects- consists of tightly packed cells that form a continuous layer and it covers surfaces and lines body cavities.
Types of epithelia-
Simple epithelia- There is three type of simple epithelium: squamous (located lining in the air sacs of lungs and walls of blood vessels and composed of flattened cells), cuboidal (located in the glands, lining of kidney tubules and composed of cube-shaped cells) and the columnar (located in the lining of small intestine and near the bottom of each cell and composed of rectangular cells) epithelium.
Pseudostratified Columnar Epithelium- It appears to be layered and has irregularly placed nuclei.
Transitional Epithelium- changes in response to tension.
Stratified Epithelia- have many layers of cells, with only the bottom layer touching the basement membrane.
Glandular Epithelia-secretes a product either into ducts or into the blood.
Cell Junctions- There is three type of junctions: the tight junctions (are like zipperlike fastenings between cells and prevent leaks) adhesion junction (permit cells to stretch and bend) gap junctions (allows small molecules and signal to pass between cells).










Integumentary System-
Skin is the most conspicuous system in the body because it covers the body. The skin has two major regions the epidermis and the dermis. Under the skin is the subcutaneous layer. The functions of the integumentary system is to project the body and help regulate body temperature.

Organ Systems-




















-Body cavities- The two major body cavities: the ventral and the dorsal cavity.
-dorsal cavity- cranial cavity (contains brain) and vertebral canal (contains spinal cord).
-ventral cavity- thoracic (contains esophagus, heart, and lungs) and abdominal cavity (contains digestive and other organs).
-Body membranes- lines cavities and the internal spaces of organs and tubes
That open to the outside. It has four types:
-Mucous membranes-
-Serous membranes-
-Synovial membranes-
-Meninges-

Homeostasis-
Homeostasis is the body’s ability to maintain a relative constancy of its internal environment by adjusting its physiological processes. All organ systems supply

Friday, February 8, 2008

The Microscope


I was able to work and view a picture of a cheek cell from an online microscope. It was fairly similar to working with a real microscope by trying to focus the cell to make it viewable. The tutorial was helpful in teaching how to work the focuses and really helpful of explaining the parts of a microscope and what it’s purpose is. The checklist was very helpful just in case I missed any steps. The cheek cell is viewing in 40x magnification.





















Parts of a Microscope and purpose-

1. Eyepiece/Oculars-where you
look through to see the image of your sample. The eyepiece helps you determine if the sample needs focusing.
2. Nosepiece-the rotating part of the microscope at the below the eyepiece tube; it holds the objectives.
3. Objective lenses- the microscope has different focuses attached to the nosepiece. It has different magnification ranging high to low letting the viewer to see their sample as close as they want.
4. Arm- The arm is where you carry the microscope with one hand and holding the base (the bottom of the microscope) with your other hand.
5. Focus knob-the knob is usually on the side of the microscope so you can focus the sample to make it more viewable. It makes the sample move high or lower to the stage.
6. Fine adjustment knob- it controls the fine focus of the image when viewing at a higher magnification.
7. Stage- it’s a place where you put the sample under the light for viewing. The focus knobs move the stage up and down to the eyepiece for viewing.
8. Iris Diaphragm-a lever that controls the amount of light going through the opening or stage.

What is a microscope?
By definition it’s an optical instrument that uses different type of lenses to produce images of small objects to be seen closer to the undetected eye. Many scientist use the microscope to see tiny organism closer like human cells, to identify minerals and other findings and also to help solve crimes today and find the causes for certain diseases. With the microscope, scientists saw the tiny germ that causes disease/illness, so the microscope is a very important tool and discovery.
History of the Microscope
It’s one of the greatest discoveries and dates back over 400 years. It was said that the first useful microscope was developed between 1590 and 1608 in the Netherlands. It’s almost impossible to know the real date of when the microscope was first discovered.
A few inventors have been credited for the microscope such as Hans Lippershey, who also developed the first telescope and his son Zacharias. It’s said that Hans was the first to make the discovery but it was his son Zacharias to continue the research. The first compound microscope was just a tube with lenses at both end and the magnification ranged from 3x to 9x. In the early 1600’s Robert Hooke improved the microscope and he was able to view a plant tissue. In the mid 1600’s Anton Van Leeuwenhoek, made the microscope lenses magnify up to 270x. He was on the first person to observe microscopic life and recorded his observations. As years went by many people are credited in improving the microscope, magnifying is even closer, making it easier to use and handle and finding even more discoveries today.

Conclusion:
The microscope is an important tool for scientific research and education. The microscope is not just for scientist trying to find cures for diseases or to find new discoveries but also for students to understand about the tiny organism and how the microscope has helped human kind, animals and our environment. People in the criminal field find the microscope useful into solving cases. Because of the microscope many cures have been found for diseases, new findings help us understand about organisms and there are always new discoveries.